Select Your Region
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a non-GMO pharmaceutical excipient with a polymer composition of 50 mol % D,L-lactide and 50 mol % Glycolide with an ester end group and no added preservatives. It is formulated by Evonik as a white to tan pelletized solid with an inherent viscosity of 0.55─0.75 dL/g in HFIP and a degradation time of 3 months max.
Fulfilled By ChemPoint
- Manufacturer: Evonik Corporation
- Product Line: LACTEL® Polymers
- Product: LACTEL® PLGE Polymers
- Industries: Pharmaceuticals
- Authorized Countries: Canada | United States
Fulfilled By ChemPoint
Documents
Package Sizes
Quantity
Overview
LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is a 100% bioresorbable PLGA-based copolymer containing a 50:50 mol ratio of D,L-Lactide and Glycolide, providing a uniform degredation rate of 3 months for controlled drug delivery. It is compatible with a range of pharmaceutical substance types, including peptides, proteins, nanoparticles, and microparticles for the formulation of long-acting injectable formulations in veterinary medicine and human generic drug formulations. As a non-solvent purified poly (D,L-lactide-co-glycolide) polymer with an amorphous nature, it exhibits enhanced adaptability and versatility in formulations with superior stability properties. LACTEL® 50:50 DL-PLGE, IV 0.55-0.75 is non-GMO certified and has no added preservatives.
Specifications
Physical state: Solid
Form: Granules
Color: White to light tan
Inherent viscosity (IV) dL/g: 0.55─0.75 (in HFIP)
Degradation time: <3 months
Crystalline Melt Transition (°C): Amorphous
Glass transition temp (°C): 45─50
Solubility (@ 5% w/w): Dichloromethane, tetrahydrofuran, ethyl acetate, chloroform, hexafluoroisopropanol, acetone
Approx. resorption (months): 1─2
Density (g/mL): 1.34
Tensile Strength (psi): 6000─8000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS No. 26780-50-7
Primary Chemistry: Poly(DL-lactide-co-glycolide)
Features & Benefits
50:50 ratio of D,L-Lactide and Glycolide
Ester end group
3-month degradation time
Biodegradable
Ideal for terminal sterilization
Bioabsorbable excipient
Suitable for use with small molecules, peptides, proteins, and other substances
Non-GMO
No added preservatives
Cost effective
Applications
Human generic drug formulations
Long-acting injectable formulations
Price sensitive applications
veterinary medicine
Related Applications
Pharmaceuticals
Related Functions
Pharmaceuticals
Have questions? Can't find the right product?
Ask our Experts
When You're Ready
Get a Quote
Ask a Question
Request a Sample
Request a Document
Document Download
Thank you
Your document download will begin shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Thank you
Thank you for your inquiry and interest in ChemPoint.
We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Thank you
Thank you for your inquiry and interest in ChemPoint.
We will respond to you shortly.
ChemPoint will not under any circumstances release personal user information to individuals or companies. All information collection is solely used to support ChemPoint customers service communications. Read our Privacy Notice.
Document Download
The document currently is provided in the following languages from the supplier at this time.
Document Download
The document currently is provided in the following languages from the supplier at this time.
Are you in the correct region?
We’ve detected that you are located in a different region than the region selected on the website. Would you like to change your region?
Current Region: English - United States
