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LACTEL® DL-PLE, IV 0.26-0.54 is a pelletized solid poly(DL-lactide) excipient formulated by Evonik for the formulation of high-quality pharmaceutical products with advanced controlled drug release. It imparts an inherent viscosity of 0.26─0.54 dL/g in chloroform and an extended degradation time of 12 months.
LACTEL® DL-PLE, IV 0.26-0.54 is an advanced lactide-containing homopolymer with medium viscosity poly(DL-lactide) and no added preservatives. It offers excellent performance in controlled drug delivery systems and medical devices in veterinary medicine and human generic drug formulations and is suitable for use with small molecules, peptides, proteins, and more. Due to its excellent bioabsorbability, it is fully metabolized by the body, offering a degradation period of 12 months.
Physical state: Solid
Form: Granules or pellets
Color: White to yellowish
Inherent viscosity (IV) dL/g: 0.26─0.54 (in chloroform)
Degradation time: <12 months
Density (g/mL): 1.25
Tensile Strength (psi): 4000─6000
Elongation (%): 3─10
Modulus (psi): 2─4x10⁵
CAS no. 26680-10-4
Primary Chemistry: Poly(DL-lactide)
D,L-Lactide homopolymer
Ester end group
No added preservatives
Bioabsorbable excipient
Suitable for use with small molecules, peptides, proteins, and other substances
Unpurified
Cost-effective
Human generic drug formulations
Long-acting injectable formulations
Price sensitive applications
veterinary medicine
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