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LACTEL® DL-PLE, IV 0.26-0.54
LACTEL® DL-PLE, IV 0.26-0.54 is a pelletized solid poly(DL-lactide) excipient formulated by Evonik for the formulation of high-quality pharmaceutical products with advanced controlled drug release. It imparts an inherent viscosity of 0.26─0.54 dL/g in chloroform and an extended degradation time of 12 months.
LACTEL® DL-PLE, IV 0.26-0.54 is an advanced lactide-containing homopolymer with medium viscosity poly(DL-lactide) and no added preservatives. It offers excellent performance in controlled drug delivery systems and medical devices in veterinary medicine and human generic drug formulations and is suitable for use with small molecules, peptides, proteins, and more. Due to its excellent bioabsorbability, it is fully metabolized by the body, offering a degradation period of 12 months.
Specifications
Physical state: Solid Form: Granules or pellets Color: White to yellowish Inherent viscosity (IV) dL/g: 0.26─0.54 (in chloroform) Degradation time: <12 months Density (g/mL): 1.25 Tensile Strength (psi): 4000─6000 Elongation (%): 3─10 Modulus (psi): 2─4x10⁵ CAS no. 26680-10-4
Primary Chemistry: Poly(DL-lactide)
Features & Benefits
D,L-Lactide homopolymer Ester end group No added preservatives Bioabsorbable excipient Suitable for use with small molecules, peptides, proteins, and other substances Unpurified Cost-effective
Applications
Human generic drug formulations Long-acting injectable formulations Price sensitive applications veterinary medicine
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