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RESOMER® RG 504 is an innovative pharmaceutical controlled-release agent containing a medium-viscosity blend of 50 mol % D,L-Lactide and 50 mol % Glycolide with a degradation period of 3 months maximum.
RESOMER® RG 504 is a lactide-based copolymer containing a purified poly(D,L-lactide-co-glycolide) (CAS no. 26780-50-7) for a minimal residual monomer content and advanced performance. RESOMER® RG 504 is specially recommended for pharmaceutical applications where controlled drug release is essential, including long-acting medication delivery systems, in-situ depot formulations, drug-loaded implants, and more, offering compatibility with a range of pharmaceutical substances, small molecules, proteins, and peptides. RESOMER® RG 504 is recommended for processing by injection molding and provides a degradation period of 3 months max.
RESOMER® RG 504 complies with FDA, GMP, EHS, DIN ISO 9001, MAF, and DMF regulations.
RESOMER® polymers have been purified for a reduced residual monomer content and are available in a variety of molecular weights and viscosity ranges to meet application needs. All polymer properties can also be adjusted to match formulation requirements.
Physical state: Solid
Form: Powder granules
Color: White to off-white
Inherent viscosity (dl/g): 0.45─0.60
Degradation time: <3 months
CAS No. 26780-50-7
Primary Chemistry: Poly(D,L-lactide-co-glycolide)
Solvent-purified co-polymer
50:50 D,L-lactide:Glycolide ratio
Alkyl ester terminated
3 month degradation period
Bioabsorbable
Biodegradable
Processed by injection molding
Completely metabolized by the body
Ideal for terminal sterilization
Suitable for use with small molecules, peptides, proteins, and other substances
Controlled release applications
Microparticles and drug-loaded implants
Long acting medication delivery formulations
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